Buyer's guide · September 2026
PEPID cost: PEPID subscription and app price for every suite, add-on and multi-year plan
The Emergency Medicine Suite is $299.95 a year. EM Complete, adult and pediatric EM with unlimited CME, is $499.95. Nursing is $214.95, pharmacy $254.95, EMS $104.95.
PEPID publishes its whole individual rate card, which almost nobody else in emergency medicine reference does. Two rules on it cost buyers real money, and both are below.
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The short answer
How much does PEPID cost?
PEPID's Emergency Medicine, Pediatric Emergency Medicine and Primary Care Plus suites each cost $299.95 for one year, $549.90 for two years or $774.85 for three, paid upfront. EM Complete, which bundles adult and pediatric emergency medicine with unlimited CME, is $499.95 a year. Nursing suites are $214.95, Pharmacist Pro with AHFS $254.95 and EMS Plus $104.95. Emergency medicine residents can pay $9.99 a month. There is a two week free trial, no free tier, and PEPID states that all sales are final.
Every figure on this page was read off PEPID's own product pages on 11 September 2026. Where a competitor publishes nothing, we say so rather than repeating a software-directory number. Last updated September 2026.
The full rate card
PEPID pricing, product by product
Thirteen published prices and one that is not. The multi-year column is where most of the money is.
| Product | Price | Term | Built for | What to know |
|---|---|---|---|---|
| Emergency Medicine Suite | $299.95 | 1 year | Emergency physicians, PAs and NPs | The flagship. Adult emergency medicine content with PEPID's drug and toxicology data, the interaction and IV compatibility checkers, calculators and pill ID. Two years paid upfront is $549.90, three years $774.85. |
| EM Complete | $499.95 | 1 year | Emergency clinicians who also see children | Adult and pediatric emergency medicine, the clinical tools and unlimited CME in one subscription. A Labor Day promotion was showing $449.95 for the first year when we checked on 11 September 2026. Plan on the regular price at renewal. |
| Pediatric Emergency Medicine Suite | $299.95 | 1 year | Pediatric emergency clinicians | Same price ladder as the adult suite: $549.90 for two years and $774.85 for three, paid upfront. |
| Primary Care Plus Ambulatory Care | $299.95 | 1 year | Primary care and urgent care | The outpatient suite, priced exactly like the emergency ones, with the same $549.90 and $774.85 multi-year terms. |
| Pharmacist Pro with AHFS | $254.95 | 1 year | Hospital and clinical pharmacists | PEPID's pharmacist product with AHFS Drug Information content. $459.90 for two years, $639.85 for three. |
| AHFS Drug Information Essentials by PEPID | $22.91 a month | Billed yearly | AHFS content on its own | Works out to $274.92 for the year, which is more than Pharmacist Pro with AHFS at $254.95. Check both at checkout before you pick the standalone one. |
| Professional Nursing or Critical Care Nursing Suite | $214.95 | 1 year | Nurses, ICU and step-down units | $379.90 for two years and $519.85 for three. An Oncology Nursing suite and student companions are sold separately. |
| Portable Drug Companion | $12.08 a month | Billed yearly | Drug reference only | About $145 for a year. Drops to $9.99 a month on a two year term and $9.30 on a three year term. The cheapest way into PEPID drug content without a full suite. |
| EMS Plus NAEMSE | $104.95 | 1 year | EMTs and paramedics | Built with the National Association of EMS Educators. $159.90 for two years, $185.85 for three. |
| Clinical Rotation Companion | $25 a month | Billed yearly | Students on rotations | $300 for the year. $22.91 a month on a two year term, $21.52 on a three year term. |
| CME add-on | $169 | 1 year | Anyone who wants credit from lookups | PEPID's own FAQ calls $169 an introductory price, so expect it to move. Already included in EM Complete. |
| Patient Medication Education add-on | $6.25 a month | Billed yearly | Printable patient drug handouts | $75 for the year, bolted onto a suite rather than sold as a product of its own. |
| Emergency medicine residents | $9.99 a month | Cancel anytime | EM residents | PEPID markets it as 33 cents a day. It is the only monthly, cancel-anytime option on the whole rate card. |
| Hospitals and residency programs | Not published | Arranged | Departments and programs | Program and institutional access is set up with PEPID directly. There is no public group rate card. |
List prices in USD from pepid.com. Promotional prices apply to the first year only. Confirm at checkout.
Is PEPID free?
No. There is no permanently free PEPID tier, no ad-supported version and no limited free drug lookup. What PEPID offers instead is a two week free trial, and its FAQ describes that trial as the full PEPID content rather than a cut-down preview. After fourteen days you subscribe or you lose access.
The trial matters more here than it does for most clinical subscriptions, because of one line further down the same FAQ: sales of all PEPID programs are final. There is no money-back window the way EBSCO offers sixty days on DynaMedex. So the trial is doing the job a refund policy does elsewhere. Run it on shift, on the phone you actually carry, and decide inside the two weeks.
If free is the requirement, the realistic options are Medscape, which is free and funded by advertising, and OpenEvidence, which is free to NPI-verified US clinicians. Neither is built around the emergency department the way PEPID is. We compare the free tiers against the paid ones in the best drug reference app guide.
The multi-year discount, and the payment plan that cancels it
PEPID's multi-year pricing is genuinely good if you pay it upfront. One year of the Emergency Medicine Suite is $299.95. Two years in one payment is $549.90, a $50 saving, and three years is $774.85, a $125 saving that brings the effective annual cost down to $258.28. The same ladder applies to the Pediatric EM and Primary Care Plus suites.
The installment plan is where that falls apart. PEPID lets you spread a multi-year term over four payments, and the totals are higher: two years in installments is $596, which is $46.10 more than paying upfront, and three years is $900, which is $125.15 more. Three years at $900 is essentially what three annual renewals at $299.95 would cost you ($899.85). The installment option gives you the long commitment without the discount that was supposed to pay for it.
So the rule is simple. If you are sure you want PEPID for three years, pay $774.85 once. If you are not sure, buy one year at $299.95 and keep auto-renewal switched off until you are. Committing $900 across four payments is the one option on the card that is worse than both.
EM Complete versus buying the suites and CME separately
EM Complete is $499.95 a year and bundles adult emergency medicine, pediatric emergency medicine, the clinical tools and unlimited CME. Priced separately, those parts are $299.95 for the Emergency Medicine Suite, $299.95 for the Pediatric Emergency Medicine Suite and $169 for the CME add-on, which is $768.90. The bundle saves $268.95 a year for anyone who would have bought all three.
For an adult-only clinician the arithmetic is closer. The Emergency Medicine Suite plus CME is $468.95, so EM Complete costs $31 more and adds the pediatric content. Most general emergency physicians see enough children to make that $31 an easy decision. A clinician in an adult-only setting, or one who already gets CME elsewhere, is better off with the suite on its own.
Two cautions. The CME add-on price is labeled introductory in PEPID's own FAQ, so the separate-purchase figure can rise. And the $449.95 EM Complete price you may see advertised is a promotion that applies to the first year only. Plan your budget on $499.95.
PEPID vs Epocrates and UpToDate on price
Against Epocrates the gap is concrete. epocrates+ is $179.99 a year, $120 less than the PEPID Emergency Medicine Suite, and Epocrates has a free tier where PEPID does not. What the extra $120 buys is setting. PEPID organizes its content around emergency and acute care, with toxicology, IV compatibility and emergency protocols in the same app, while Epocrates is a general drug lookup with a disease reference added on the paid tier. Our Epocrates cost breakdown covers exactly what that tier includes.
Against UpToDate only one side of the comparison can be stated. Wolters Kluwer publishes no individual UpToDate price at any tier and quotes only after you pick a country and a professional role, so any PEPID vs UpToDate price table you find online is filling one column with a guess. What we can tell you is every route to access that does exist, on our UpToDate subscription cost page.
The fairer priced comparison for a broad reference is DynaMedex at $599 a year, or ClinicalKey Essentials from Elsevier at $299 a year. Both cost the same as PEPID or more, and neither is built around the emergency department. That, more than price, is the argument for PEPID if you work in one.
Where a reference stops
PEPID's interaction checker and IV compatibility checker are good, and they share the limitation every reference has: they answer the question you think to ask. At 4 a.m. with a full board, the interaction that causes harm is usually the one nobody had a reason to look up, on a patient whose medication list came in on a crumpled sheet.
Prescriber.io works at a different moment. You enter the prescribing scenario once, and it checks interactions across the whole list, flags contraindications and allergy blockers, and surfaces renal and hepatic dose adjustments together in one card with cited sources. It is decision support for licensed clinicians, priced per seat from $29 to $59 a month, and it sits alongside a reference like PEPID rather than replacing it. You review every flag, verify against official sources, and sign.
Which one to buy
Four recommendations, stated plainly
Most buyers only need to choose between two products and one payment option.
You work a mixed ED: buy EM Complete
If children come through your doors, the adult suite plus the pediatric suite plus CME would cost $768.90 bought separately. EM Complete bundles all three for $499.95. For a general emergency physician that is the easiest call on the rate card, and the only reason not to make it is that you never see kids.
Adult-only and paying yourself: three years upfront
The Emergency Medicine Suite at $774.85 for three years works out to $258.28 a year against $299.95 renewing annually, a $125 saving. Pay it in one go. The four-payment plan for the same three years costs $900, which throws the discount away entirely.
Resident: the $9.99 monthly plan
It is the one PEPID product you can cancel at any time, and sales on the annual plans are final. Before paying anything, ask your program: residency access is arranged with PEPID directly, and plenty of programs already cover it.
Pharmacist or nurse: price the alternatives first
Pharmacist Pro with AHFS at $254.95 competes with Lexidrug at $29.99 a month for one package. The nursing suites at $214.95 compete with Davis's Drug Guide at $39.99 a year. PEPID's advantage is emergency and critical care depth. If that is not your setting, the cheaper drug reference is usually the better buy.
The wider market
What the references a PEPID buyer weighs actually publish
Seven publish a price. UpToDate publishes nothing. Read the scope column before the price column.
| Tool | Vendor | Published US price | Scope | Verified |
|---|---|---|---|---|
| PEPID Emergency Medicine Suite | PEPID, LLC | $299.95 a year | Emergency medicine reference, drugs, toxicology | pepid.com, Sep 2026 |
| PEPID EM Complete | PEPID, LLC | $499.95 a year | Adult and pediatric EM plus CME | pepid.com, Sep 2026 |
| epocrates+ | athenahealth | $179.99 a year or $24.99 a month | Broad drug and disease reference | US App Store, Sep 2026 |
| UpToDate Lexidrug | Wolters Kluwer | $29.99 a month, one package | Drug compendium | US App Store, Sep 2026 |
| ClinicalKey Essentials | Elsevier | $299 a year or $29 a month | Clinical overviews, drug monographs, books | Elsevier store, Sep 2026 |
| DynaMedex | EBSCO | $599 a year | Broad clinical reference with Micromedex drug content | dynamedex.com store, Sep 2026 |
| Sanford Guide All Access | Antimicrobial Therapy, Inc. | $79.99 a year | Infectious disease only | sanfordguide.com, Sep 2026 |
| UpToDate | Wolters Kluwer | Nothing published, any tier | Broad clinical reference | UpToDate store, Sep 2026 |
| Prescriber.io | Prescriber.io | $29 to $59 per clinician a month | Prescribing checks at the point of signing | Our own pricing page |
Each vendor's own published figures as of September 2026. We do not repeat software-directory numbers the vendor never published.
The pattern in that table holds across the whole market. Products bought by one clinician on a personal card publish a price, because nobody buys what they cannot see. Products sold to a procurement department publish nothing, because a public number would cap every negotiation. PEPID sits firmly in the first group for individuals and moves to the second the moment a whole department or residency program is buying, which is why its group access is arranged rather than listed.
If you are pricing a department purchase, the published individual rate is your ceiling. No group deal should cost more per clinician than $299.95 a year, and our guide to institutional and group license pricing covers how to get the quote in a form you can compare.
Before you pay
Four steps that change the number on the invoice
The first costs one email. The third saves up to $125.15 on the same three years.
Check your department, program and ACEP membership
PEPID sells to hospitals and residency programs, and ACEP lists a 15 percent member discount on one year of the Emergency Medicine or Pediatric Emergency Medicine suite. One email to your chief resident or department admin can take the price to zero.
Run the two week trial on the device you will actually use
PEPID's trial is the full content, and its FAQ is blunt that sales of all PEPID programs are final. The trial is your refund policy. Use it on shift, on your own phone, and decide inside the fourteen days.
Pay multi-year upfront, never in installments
Two years upfront is $549.90; the same two years in four payments is $596. Three years upfront is $774.85; in four payments it is $900, which is what three separate annual renewals would cost you anyway. The installment plan is a financing product, not a discount.
Decide on CME separately
The $169 CME add-on is only worth buying if you would otherwise pay for credit. Medscape and Epocrates both run accredited CME catalogs at no charge, so compare the format you will actually complete before you add it.
On the CME question specifically, we compare what free and paid credit actually require in Epocrates CME cost vs Medscape and UpToDate.
Straight answers
Questions people actually search about PEPID pricing
How much does PEPID cost?
PEPID's Emergency Medicine Suite costs $299.95 for one year, the same as its Pediatric Emergency Medicine and Primary Care Plus Ambulatory Care suites. EM Complete, which bundles adult and pediatric EM with unlimited CME, is $499.95 a year. Nursing suites are $214.95, Pharmacist Pro with AHFS is $254.95 and EMS Plus is $104.95, all read from pepid.com in September 2026.
How much is a PEPID subscription per month?
Most PEPID products are sold annually, not monthly. The exception is the emergency medicine resident plan at $9.99 a month, which can be cancelled at any time. PEPID quotes a few annual products as a monthly figure, such as the Portable Drug Companion at $12.08 a month, but those are billed as one yearly charge of about $145.
Is PEPID free?
No. PEPID has no permanently free tier. It offers a two week free trial of the full content, and after that every product is a paid subscription. That puts it alongside Epocrates+, Sanford Guide and DynaMedex as a paid reference, and apart from Medscape and OpenEvidence, which are free and funded by advertising.
Does PEPID have a free trial?
Yes. PEPID offers a two week free trial, and its FAQ describes the trial as the full PEPID content so you can test the functionality in depth. Take it seriously, because PEPID also states that sales of all its programs are final. The trial is effectively the only way to find out whether it suits you before you pay.
Can I get a refund on PEPID?
Generally no. PEPID's FAQ states that sales of all PEPID programs are final and points buyers to the free trial instead. That matters most on the multi-year terms, where you can commit $774.85 for three years in one payment. Use the trial fully, and turn off auto-renewal if you are unsure you will want the second year.
How do I cancel PEPID auto-renewal?
Log in to your PEPID account, open your subscription and switch off the auto renew option. If you cannot find it, PEPID says its support team will disable auto-renewal on request, no questions asked, by email at support@pepid.com or through live chat. Do this before the renewal date, because a renewed annual term falls under the no-refund policy.
Is there a PEPID discount for ACEP members?
Yes. ACEP lists a 15 percent discount for members on a one year subscription to PEPID's Emergency Medicine Suite or Pediatric Emergency Medicine Suite, which takes the $299.95 list price to roughly $255. The discount applies to the one year term, so compare it against the three year upfront price of $774.85, which is $258.28 a year without any membership.
How much is PEPID for residents?
PEPID sells emergency medicine residents a plan starting at $9.99 a month that can be cancelled at any time, which PEPID frames as 33 cents a day. Residency programs can also arrange access for a whole class directly with PEPID. Ask your program coordinator before buying, because a program subscription makes the personal one unnecessary.
Does PEPID include CME?
Only if you buy it. CME is a $169 a year add-on, which PEPID's FAQ calls an introductory price, or it comes included in EM Complete at $499.95. For an emergency physician who sees children, EM Complete is the cheaper route to CME than adding it to a single suite, because the bundle also includes the pediatric content.
Is PEPID cheaper than UpToDate?
PEPID publishes its prices and UpToDate does not, so only PEPID's side of that comparison can be stated. The Emergency Medicine Suite is $299.95 a year. Wolters Kluwer publishes no individual UpToDate price at any tier and quotes only after you choose a country and role. For a priced alternative, DynaMedex lists at $599 a year and epocrates+ at $179.99.
Is PEPID better than Epocrates?
They are built for different settings. PEPID is organized around emergency and acute care, with toxicology, IV compatibility and emergency protocols in the suite. Epocrates is a fast general drug lookup with a free tier and epocrates+ at $179.99 a year. An ED clinician usually gets more from PEPID; an outpatient prescriber usually gets enough from Epocrates at $120 a year less.
What does every PEPID suite include?
PEPID lists the same core tools in every suite: dosing and medical calculators, a drug interactions checker, an IV compatibility checker, pill identification, a lab manual, illustrations and radiographic images, medical videos, and notes and favorites. What changes between suites is the clinical content, emergency, pediatric, primary care, nursing or pharmacy, not the toolset.
Go deeper
What the other references cost, and what to run alongside them
UpToDate subscription cost
The broad reference that publishes no price at any tier.
CostEpocrates cost
epocrates+ at $179.99 a year, and what the free tier keeps.
CostDynaMed and DynaMedex cost
$599 a year, a 30 day trial and a 60 day money-back window.
ToolIV compatibility checker
Y-site and admixture checks on the drugs you are running.
BuyingInstitutional license pricing
How quote-only contracts get negotiated, seat by seat.
GuideBest drug reference app
The broad compendiums, scored on what each is actually for.
We publish every per-seat rate we charge.
Prescriber.io checks interactions, flags contraindications, surfaces renal and hepatic dosing and suggests guideline-based alternatives, with cited sources. You review, verify, and sign.
Decision-support for licensed clinicians. Prescriber.io does not diagnose or prescribe autonomously and is not a substitute for professional clinical judgment. Always verify against official sources. PEPID is a trademark of PEPID, LLC; Prescriber.io is not affiliated with PEPID.