IV room buyer's guide
Trissel's Handbook on Injectable Drugs price, the $49.99 app and Trissel's 2 online
Trissel's is now sold as ASHP Injectable Drug Information 2025: $473 in print, $359 for ASHP members, and the store sells it to members. The licensed app is $49.99 a year.
Below is every current way to pay for it, the King Guide alternative, and which one fits an IV room, an infusion pharmacy or one pharmacist.
Press Run check for the interaction, contraindication, dosing and alternatives on this pair.
Not matched, so not checked: .
Nothing on this pair matched a row in the reference tables behind this check. That is not a clearance: it means these references do not name this combination.
Guideline-based alternatives
That was your demo check, run on the same references the desk uses. The desk adds renal dosing against an estimated clearance, hepatic review, unlimited checks, saved history and your sign-off on every card.
The on-page check covers five prescribing scenarios and never invents clinical output, so it will not produce a card for this pair.
The full Prescriber.io desk checks any regimen against interactions, contraindications, and renal or hepatic dosing, with cited sources for you to verify.
Interaction
Contraindication / allergy check
Dosing guidance (renal / hepatic)
Guideline-based alternatives
Decision support. You verify against official sources and sign.
Clinician in the loopDecision support for licensed clinicians. Prescriber.io does not diagnose or prescribe and is not a substitute for professional clinical judgment.
The short answer
How much is Trissel's Handbook on Injectable Drugs?
The current Trissel's Handbook on Injectable Drugs is ASHP Injectable Drug Information 2025, a 1,800 page hardcover (ISBN 978-1-58528-743-7) that lists at $473 in print or eBook and costs $359 for ASHP members. The ASHP store sells it to current members only, so a pharmacist who is not a member pays $375 in dues on top. The licensed Handbook on Injectable Drugs iPhone app, built on the same 2025 content, costs $49.99 a year with no membership. Online, the Trissel's 2 database sits inside Micromedex and Lexidrug for hospitals and inside Elsevier's Clinical Pharmacology at $650 a year for individuals.
Figures read on the ASHP store, the US App Store, ASHP's 2026 membership application, kingguide.net and Elsevier's store. No reseller estimates.
What the 2025 edition holds
What you are paying for in ASHP Injectable Drug Information 2025
The same content feeds the print book, the eBook and the licensed app.
400+ parenteral monographs
Each drug listed by generic name with brand names cross-referenced, plus preparation, storage and administration details.
24,500+ compatibility pairs
Tabulated results from published studies, the reason pharmacists buy the book in the first place.
Four tables per drug
Solution, additive, syringe and Y-site compatibility, the layout the app keeps from the print edition.
S4S standard concentrations
The 2025 edition adds ASHP Standardize 4 Safety concentrations, including new adult and pediatric PCA and epidural standards.
3,700+ references
Every entry traces back to the published literature, which is what makes it defensible in a policy or a P&T packet.
AHFS classification
The full AHFS Pharmacologic-Therapeutic Classification is included, so the book lines up with AHFS Drug Information.
Solution
Additive
Syringe
Y-site
Layout only. Compatibility results are the publisher's licensed data.
Four tables per drug, the reason IV rooms keep buying it
Every monograph breaks the published evidence into solution, additive, syringe and Y-site compatibility, with the concentration, container and reference behind each result. That is what a pharmacist checking a second infusion through one line needs, and it is why the book has sat on sterile compounding counters for decades.
The app keeps the same four-table layout and adds icons for quick scanning. We do not reproduce any results here: they are the publisher's licensed data, and a wrong pair copied onto a web page is a patient-safety problem.
Every way to pay
Trissel's Handbook and IV compatibility prices, format by format
Six published prices you can pay today and one route that is quoted to hospitals.
| Format | Price | Term | Built for | What to know |
|---|---|---|---|---|
| ASHP Injectable Drug Information 2025 (print) | $473 list, $359 ASHP member | One edition, bought once | IV rooms, infusion pharmacies, pharmacy libraries | 1,800 page hardcover, ISBN 978-1-58528-743-7. This is the current Trissel's Handbook under its new name. The ASHP store showed "this item can only be purchased by current members" when we read it. |
| ASHP Injectable Drug Information 2025 (eBook) | $473 list, $359 ASHP member | One edition, bought once | Pharmacists who want the full text on a laptop | Offered as a format option on the same ASHP store listing at the same price range, with the same members-only notice. |
| Handbook on Injectable Drugs app (iOS) | $49.99 a year | Auto-renewing annual | One pharmacist or nurse who needs it on a phone | Sold by Skyscape Medpresso under license from ASHP, content licensed from the 2025 edition. Free download with sample content. No ASHP membership needed. Rated 4.7 from 12 ratings. |
| Pediatric Injectable Drugs 12th ed. (Teddy Bear Book) | $225 list, $171 ASHP member | One edition, bought once | NICU, PICU and pediatric infusion pharmacists | 1,104 pages, 2024, ISBN 978-1-58528-718-5. The pediatric companion volume, also sold to current members only. |
| Clinical Pharmacology (Elsevier) | $650 a year | Annual, one plan | Individuals who want Trissel's 2 data online plus a full drug database | The only individual online plan we found that includes IV compatibility from the Trissel's 2 database at a published price. |
| King Guide Online Edition | $475 single user, $599 to $2,100 sites | Annual, tiered by bed count | Buyers who want a published price and an independent dataset | Not Trissel's data. The King Guide to Parenteral Admixtures is a separate reference with its own editorial rules. |
| Micromedex IV Compatibility, Lexidrug Trissel's module | Not published | Institutional contract | Hospitals and health systems | Both run on the Trissel's 2 Clinical Pharmaceutics Database. If you work in a hospital, check these before buying anything. |
US prices, read at each vendor in September 2026. The price at checkout is the one that binds.
Is Trissel's Handbook still published?
Yes, under a new name. ASHP now publishes the book as ASHP Injectable Drug Information, and the 2025 edition is current. Pharmacists still say "Trissel's" after Lawrence A. Trissel, who wrote the early editions of the Handbook on Injectable Drugs, and most booksellers still index the old title. That is the trap: search Amazon or a used-book site for Trissel's and the top listings are the 16th to 20th editions, printed between 2010 and 2018.
The 2025 edition carries more than 400 parenteral monographs, over 24,500 compatibility pairs and more than 3,700 references. It adds ASHP's Standardize 4 Safety concentrations, including new adult and pediatric PCA and epidural standards, and the full AHFS classification. An old copy lacks every drug and every study published since it went to press, which is why a used 18th edition at a fraction of the price is a false saving for anyone who will act on it.
Can non-members buy ASHP Injectable Drug Information?
Not from ASHP. Both store listings we read in September 2026, the hardcover and the print-or-eBook listing, show the notice "this item can only be purchased by current members". The member price is $359 against a $473 list, a saving ASHP puts at $114 or more.
So the real first-year price of the book depends on your membership. A practicing pharmacist who is not a member pays $375 in 2026 dues plus $359, which is $734. That is almost fifteen years of the $49.99 app. The book is worth that premium when you want the membership anyway, or when the copy will serve a whole compounding team rather than one person.
The real price of the book
ASHP Injectable Drug Information price with 2026 dues added
The store sells the 2025 edition to members, so year one costs dues plus $359.
| You are | 2026 ASHP dues | Book, member price | First year total |
|---|---|---|---|
| Pharmacist (Active Full Member) | $375 | $359 | $734 |
| Resident or first year new graduate | $94 | $359 | $453 |
| Second year post-graduate, non-resident | $188 | $359 | $547 |
| Pharmacy technician | $60 | $359 | $419 |
| Pharmacy student, P2 to P4 | $60 | $359 | $419 |
Dues from ASHP's 2026 membership application. The same membership also unlocks the member price on AHFS Drug Information, which ASHP also sells to members only, so buyers who need both books recover the dues faster.
Is there a Trissel's app, and is $49.99 a year worth it?
Yes. The Handbook on Injectable Drugs app on the US App Store is sold by Skyscape Medpresso under license from ASHP. Its description says the content is licensed from ISBN 9781585287437, the 2025 edition, and calls it the 25th edition. It is a free download with sample content, and full access is a yearly subscription at $49.99 that renews unless you switch it off at least 24 hours before the term ends. It holds 4.7 stars, but from only 12 ratings.
For a single pharmacist, nurse or infusion specialist, the app is the cheapest current way to carry Trissel's-lineage data. It needs no membership, it costs about a tenth of the book's list price, and it keeps the four compatibility tables per drug. The trade-off is that it is one person's license on one Apple ID. A department that needs a shared reference is better served by the print copy or by an institutional database.
Is Trissel's available online?
Yes, but not as a standalone ASHP website you can subscribe to. The online form is the Trissel's 2 Clinical Pharmaceutics Database, and it reaches clinicians through three products. Merative's Micromedex IV Compatibility and Wolters Kluwer's Trissel's module for Lexidrug both run on it, and both are sold to hospitals without a published price. Elsevier's Clinical Pharmacology includes Trissel's 2 IV compatibility in its single $650 a year individual plan, which also covers monographs, interactions and calculators.
If you are in a hospital, the cheapest route is almost always the one you already have. Our IV compatibility checker guide explains how to find out whether your Micromedex or Lexidrug login already includes the IV tool, and the Lexicomp vs Micromedex comparison covers the rest of what each database does. If you are pricing Clinical Pharmacology as a personal purchase, the Clinical Pharmacology subscription cost guide covers its trial and renewal terms.
The independent alternative
King Guide to Parenteral Admixtures price and how it differs from Trissel's
The King Guide is the other long-running IV compatibility reference, published independently by King Guide Publications. It only uses data published in peer-reviewed journals or supplied by the manufacturer, and it lists about 610 injectable drug monographs with quarterly updates.
It is also the only reference in this category with an open rate card. A single user pays $475 a year, which is more than the $359 member price of the ASHP book and nearly ten times the Trissel's app. What you get for that is a second, independent dataset and a clear license for one named user.
Many hospital pharmacies keep both, because when two good sources disagree on a pair, that disagreement is itself useful information.
| King Guide Online Edition license | Per year |
|---|---|
| Single user license | $475 |
| Educational institution (no beds) | $599 |
| Site license, under 250 beds | $760 |
| Site license, 251 to 1,500 beds | $1,100 |
| Site license, more than 1,500 beds | $2,100 |
Which one to buy
Four recommendations, by where you work
Most buyers are choosing between the book, the app and an online database.
You work alone or float between sites. Buy the $49.99 app
It carries content licensed from the 2025 edition, needs no ASHP membership and costs less than a seventh of the list price of the book. For one person it is the cheapest current way to own Trissel's-lineage data.
You run an IV room or a home infusion pharmacy. Buy the print edition
A desk copy that every technician and pharmacist on the shift can open is still how many sterile compounding areas work. At $359 for members it is also cheap next to a single compounding error.
You want the data online, updated, with a drug database around it. Price Clinical Pharmacology
At $650 a year it is the only individual plan we found with Trissel's 2 IV compatibility at a published price, plus monographs, interactions and calculators.
You work in a hospital. Ask pharmacy informatics first
Micromedex and Lexidrug both license Trissel's 2 data for their IV compatibility tools. If your hospital holds either, the answer you need is already behind your work login.
Pediatric and neonatal lines need a second book
ASHP Injectable Drug Information is written around adult practice. For NICU and PICU work, ASHP publishes Pediatric Injectable Drugs, the Teddy Bear Book, now in its 12th edition (2024, 1,104 pages) at $225 list or $171 for members, sold to members only. Pediatric teams that also need oral and neonatal dosing usually pair it with a dosing handbook; our guide to the Pediatric and Neonatal Dosage Handbook price compares the print handbook with the app routes.
The wider market
Trissel's vs King Guide, Clinical Pharmacology and Micromedex
Where each IV compatibility source gets its data and what it publishes as a price.
| Source | Data behind it | Published US price | Format |
|---|---|---|---|
| ASHP Injectable Drug Information (Trissel's) | ASHP monographs, 24,500+ pairs | $473 book ($359 member), $49.99 a year app | Print, eBook, iOS app |
| King Guide to Parenteral Admixtures | Independent, peer-reviewed only | $475 a year single user | Online and print |
| Clinical Pharmacology | Trissel's 2 database | $650 a year | Online, app with login |
| Micromedex IV Compatibility | Trissel's 2 database | Not published | Hospital license |
| Lexidrug Trissel's IV module | Trissel's 2 database | Not published | Enterprise module |
| Prescriber.io | Not an IV compatibility source | $24 to $37 per clinician a month | Prescription checks at signing |
Where an IV reference stops and a prescription check starts
Trissel's answers one question very well: can these two things share a line or a syringe. It does not look at the rest of the patient. Prescriber.io is not an IV compatibility source and does not answer that question. It works one step earlier, when the order is written: you enter the prescribing scenario once, and it checks interactions across the whole medication list, flags contraindications and allergy blockers, and surfaces renal and hepatic dose adjustments with cited sources. Per seat it runs $24 to $37 a month billed annually, and the clinician reviews every flag and signs.
Before you pay
Four checks before you buy Trissel's
The first one saves most people from buying a 2014 edition by mistake.
Search the new name, not the old one
Sellers still list "Trissel's Handbook on Injectable Drugs" editions from 2010 to 2018. The current edition is sold as ASHP Injectable Drug Information 2025, ISBN 978-1-58528-743-7.
Check the edition year before you pay
Compatibility data changes as new studies and products appear. A cheap used 17th or 18th edition is missing years of pairs and the S4S standard concentrations.
Price membership into the book
A pharmacist who is not an ASHP member pays $375 in dues plus $359, which is $734 in year one. That only makes sense if you want the membership anyway.
Turn off auto-renew if you buy the app once
The $49.99 subscription renews each year unless you switch it off at least 24 hours before the term ends in your Apple ID settings.
Straight answers
Questions people search about Trissel's Handbook
How much is Trissel's Handbook on Injectable Drugs?
The current edition, sold as ASHP Injectable Drug Information 2025, lists at $473 in print or eBook and costs $359 for ASHP members. The ASHP store sells it to current members. The licensed Handbook on Injectable Drugs app costs $49.99 a year on iPhone with no membership needed.
Is Trissel's Handbook still published?
Yes, under a different name. ASHP now publishes the book as ASHP Injectable Drug Information, and the 2025 edition is current, with 400+ monographs and 24,500+ compatibility pairs. Pharmacists still call it Trissel's after Lawrence A. Trissel, who wrote the early editions of the Handbook on Injectable Drugs.
What is the latest edition of Trissel's Handbook on Injectable Drugs?
The latest edition is ASHP Injectable Drug Information 2025, a 1,800 page hardcover with ISBN 978-1-58528-743-7. The App Store listing for the licensed app describes it as the 25th edition. Older copies titled Handbook on Injectable Drugs, up to the 20th edition, are out of date.
Is there a Trissel's app?
Yes. The Handbook on Injectable Drugs app on the US App Store, sold by Skyscape Medpresso under license from ASHP, carries content from the 2025 edition. It is a free download with sample content and a $49.99 yearly subscription that renews automatically. It shows solution, additive, syringe and Y-site tables for each drug.
Is Trissel's available online?
Yes, through licensed databases rather than a standalone site. Micromedex IV Compatibility and the Lexidrug Trissel's module both run on the Trissel's 2 Clinical Pharmaceutics Database, sold to institutions. For an individual, Elsevier's Clinical Pharmacology includes Trissel's 2 IV compatibility at $650 a year.
Can non-members buy ASHP Injectable Drug Information?
Not from the ASHP store, based on the product pages we read in September 2026, which show that the 2025 edition can only be purchased by current members. Non-members can still buy the licensed $49.99 app, or look for the book through booksellers, where old editions are far more common than the current one.
What is the difference between Trissel's and the King Guide?
They are separate datasets from separate publishers. Trissel's lineage content comes from ASHP and powers Micromedex and Lexidrug through Trissel's 2. The King Guide to Parenteral Admixtures is published independently, only uses peer-reviewed or manufacturer data, and publishes its price: $475 a year for a single user.
Does Micromedex use Trissel's?
Yes. Merative states that Micromedex IV Compatibility is powered by the Trissel's 2 Clinical Pharmaceutics Database, drawing on more than 4,600 references. Wolters Kluwer sells a Trissel's IV compatibility module for Lexidrug built on the same database. Neither vendor publishes a price.
Is it safe to use an older edition of Trissel's?
It is a risk for a working IV room. Each edition adds new compatibility pairs, new products and updated references, and the 2025 edition adds ASHP Standardize 4 Safety concentrations. An old edition will simply lack data on newer drugs, so use a current source for anything you will act on.
What is the Teddy Bear Book?
It is Pediatric Injectable Drugs, ASHP's pediatric companion to the injectable drug handbook, known by its cover. The 12th edition (2024) has 1,104 pages and lists at $225, or $171 for ASHP members, and the store sells it to current members.
Go deeper
Other pharmacy references, priced
IV compatibility checker
Micromedex, Lexidrug and King Guide access, compared.
CostAHFS Drug Information price
The other ASHP book sold to members, and its $99.99 app.
CostClinical Pharmacology subscription cost
$650 a year with Trissel's 2 IV data included.
PlansLexidrug subscription plans
What $29.99 a month buys, package by package.
CostMicromedex subscription cost
Why there is no public price, and what hospitals pay for.
ToolDrug interaction checker
Checks the whole medication list at the point of prescribing.
Trissel's checks the line. We check the prescription.
Prescriber.io checks interactions, flags contraindications, surfaces renal and hepatic dosing and suggests guideline-based alternatives, with cited sources. You review, verify, and sign.
Decision-support for licensed clinicians. Prescriber.io does not diagnose or prescribe autonomously, does not provide IV compatibility results, and is not a substitute for professional clinical judgment. Always verify against official sources. ASHP Injectable Drug Information and AHFS are trademarks of ASHP; Trissel's is a trademark of its owner. Prescriber.io is not affiliated with ASHP, Skyscape, King Guide Publications, Elsevier, Merative or Wolters Kluwer.